Across TCGA cell cohorts, TSSK2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSSK2-associated genes across cancer lineages are OR10A5, ELSPBP1, and FAM71A. Each is linked with TSSK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSSK2-to-partner and partner-to-TSSK2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSSK2→partner) and Y-score (partner→TSSK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR10A5 →	+0.036	+4.029	<.001	.009	3	1
OVARY	ELSPBP1 →	+0.137	+4.029	.006	.009	3	1
LARGE_INTESTINE	FAM71A →	+0.043	+2.938	.009	.007	3	1
LARGE_INTESTINE	GALR3 →	+0.085	+2.865	.006	.004	2	1
LARGE_INTESTINE	GAS2L2 →	+0.115	+3.070	<.001	.002	2	1
LARGE_INTESTINE	RAB44 →	+0.076	+3.743	.002	.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

TSSK2 survival (RNA) · tumor vs normal (RNA) · all TSSK2 data types