Across TCGA patient cohorts, TSSC4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,279 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TSSC4-associated genes across cancer lineages are ARFIP2, RRP8, and TIMM10B. Each is linked with TSSC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSSC4-to-partner and partner-to-TSSC4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSSC4→partner) and Y-score (partner→TSSC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARFIP2 →	+0.479	+0.287	<.001	<.001	3	3
BRCA	RRP8 →	+0.491	+0.257	<.001	<.001	3	3
OV	TIMM10B →	+0.473	+0.255	<.001	.003	3	3
BRCA	SIRT3 →	+0.579	+0.283	.001	<.001	3	3
BRCA	RIC8A →	+0.488	+0.187	<.001	.009	3	3
LSCC	NAP1L4 →	+0.449	+0.300	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,279 associations by consensus.

Exploration

TSSC4 survival (RNA) · tumor vs normal (RNA) · all TSSC4 data types