TSPYL6

Across TCGA cell cohorts, TSPYL6 mutation is significantly associated with the mutation status of many other genes, with 1,297 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPYL6-associated genes across cancer lineages are ATN1, TSHZ2, and UGT2A3. Each is linked with TSPYL6 in more than 3 cancer types. Because this analysis shows association rather than direction, both TSPYL6-to-partner and partner-to-TSPYL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATN1 grouped by TSPYL6-low versus TSPYL6-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL6→partner) and Y-score (partner→TSPYL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ATN1 →	+4.014	+4.969	.008	.008	1	4
BLOOD_Lymphoma	TSHZ2 →	+4.014	+4.969	.008	.008	1	3
SKIN	UGT2A3 →	+5.053	+4.239	.007	.007	1	3
SKIN	PPFIA3 →	+2.830	+3.548	.009	.009	1	3
BLOOD_Leukemia	TNRC18 →	+2.197	+3.280	.007	.007	1	3
LARGE_INTESTINE	PLA2G6 →	+2.630	+3.047	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,297 associations by consensus.

ATN1 by TSPYL6 expression — BLOOD_Lymphoma

Explore this box plot interactively →