TSPYL5

Across TCGA patient cohorts, TSPYL5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,082 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TSPYL5-associated genes across cancer lineages are ZNF454, MAP10, and GAREM2. Each is linked with TSPYL5 in more than 4 cancer types. Because this analysis shows association rather than direction, both TSPYL5-to-partner and partner-to-TSPYL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPYL5 versus ZNF454 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL5→partner) and Y-score (partner→TSPYL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF454 →	+0.536	+0.569	<.001	<.001	3	5
OV	MAP10 →	+0.781	+0.787	<.001	<.001	3	5
BRCA	GAREM2 →	+0.898	+0.938	<.001	<.001	3	4
BRCA	AKR1E2 →	+0.907	+0.775	.001	<.001	3	4
LSCC	WNK3 →	+0.780	+1.011	<.001	<.001	3	4
BRCA	PPIAP35 →	+0.764	+1.131	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,082 associations by consensus.

TSPYL5 vs ZNF454 — UCEC

Explore this scatter interactively →