TSPYL5

Across TCGA cell cohorts, TSPYL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,299 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TSPYL5-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Establishment of protein localization to organelle. Each is linked with TSPYL5 in more than 7 cancer types. Because this analysis shows association rather than direction, both TSPYL5-to-partner and partner-to-TSPYL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by TSPYL5-low versus TSPYL5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL5→partner) and Y-score (partner→TSPYL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.112	+2.127	<.001	.003	3	8
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.109	+2.127	<.001	.003	3	8
STOMACH	Establishment of protein localization to organelle →	+0.048	+2.590	<.001	<.001	3	8
BLOOD_Lymphoma	Aerobic respiration →	+0.070	+1.218	<.001	.002	3	8
BLOOD_Lymphoma	Proton motive force-driven ATP synthesis →	+0.077	+1.240	<.001	.001	3	7
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.076	+0.872	<.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,299 associations by consensus.

Negative regulation of myoblast fusion by TSPYL5 expression — STOMACH

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