Across TCGA patient cohorts, TSPYL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,542 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TSPYL2-associated proteins across cancer lineages are SEPTIN7, SORBS3, and MMP2. Each is linked with TSPYL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TSPYL2-to-partner and partner-to-TSPYL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL2→partner) and Y-score (partner→TSPYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SEPTIN7 →	+0.322	+0.497	<.001	<.001	3	6
OV	SORBS3 →	+0.452	+0.847	.002	.001	3	6
BRCA	MMP2 →	+0.607	+0.548	.001	.001	3	6
LUAD	RRBP1_T275 →	-0.581	-0.546	<.001	<.001	3	6
OV	DCN →	+0.935	+0.904	<.001	<.001	3	6
PDAC	DDX21_S89 →	-0.857	-0.401	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,542 associations by consensus.

Exploration

TSPYL2 survival (RNA) · tumor vs normal (RNA) · all TSPYL2 data types