Across TCGA patient cohorts, TSPYL2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,515 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSPYL2-associated genes across cancer lineages are PSMD11, DNAJC27, and MAP4K3. Each is linked with TSPYL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPYL2-to-partner and partner-to-TSPYL2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL2→partner) and Y-score (partner→TSPYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSMD11 →	+0.660	+0.551	<.001	<.001	3	2
UCEC	DNAJC27 →	+0.501	+0.688	<.001	.005	3	2
UCEC	MAP4K3 →	+0.517	+0.754	.001	<.001	3	2
UCEC	ARID3A →	+1.065	+0.745	<.001	<.001	3	2
UCEC	SUPT7L →	+0.435	+0.534	.002	.005	3	2
UCEC	MBTPS2 →	+0.813	+0.757	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,515 associations by consensus.

Exploration

TSPYL2 survival (RNA) · tumor vs normal (RNA) · all TSPYL2 data types