Across TCGA cell cohorts, TSPYL2 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPYL2-associated genes across cancer lineages are OR10K2, PABPC1L2A, and OR10T2. Each is linked with TSPYL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPYL2-to-partner and partner-to-TSPYL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPYL2→partner) and Y-score (partner→TSPYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1
BREAST	PABPC1L2A →	+0.083	+5.169	<.001	.005	3	1
BREAST	OR10T2 →	+0.183	+5.781	<.001	.001	3	1
BLOOD_Lymphoma	REG3G →	+0.026	+4.867	.004	.009	3	1
BLOOD_Lymphoma	C1orf87 →	+0.056	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR1M1 →	+0.019	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

TSPYL2 survival (RNA) · tumor vs normal (RNA) · all TSPYL2 data types