TSPY8

Across TCGA cell cohorts, TSPY8 RNA expression is significantly associated with the mutation status of many other genes, with 87 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TSPY8-associated genes across cancer lineages are PHRF1, LRRC59, and POLR3A. Each is linked with TSPY8 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPY8-to-partner and partner-to-TSPY8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHRF1 grouped by TSPY8-low versus TSPY8-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPY8→partner) and Y-score (partner→TSPY8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PHRF1 →	+5.357	+0.023	.003	<.001	3	2
SOFT_TISSUE	LRRC59 →	+5.369	+0.015	.004	.002	3	1
SOFT_TISSUE	POLR3A →	+4.369	+0.016	.008	<.001	3	1
SOFT_TISSUE	GAA →	+4.369	+0.024	.008	<.001	3	1
SOFT_TISSUE	ZNF101 →	+5.369	+0.022	.004	<.001	3	1
SOFT_TISSUE	ZNF749 →	+4.369	+0.016	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

PHRF1 by TSPY8 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →