Across TCGA cell cohorts, TSPY3 RNA expression is significantly associated with the mutation status of many other genes, with 49 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TSPY3-associated genes across cancer lineages are GLI3, TRIM67, and GGA3. Each is linked with TSPY3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPY3-to-partner and partner-to-TSPY3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPY3→partner) and Y-score (partner→TSPY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	GLI3 →	+4.392	+0.040	.004	<.001	3	1
SOFT_TISSUE	TRIM67 →	+4.977	+0.050	.002	<.001	3	1
SOFT_TISSUE	GGA3 →	+3.977	+0.033	.007	<.001	3	1
SOFT_TISSUE	CGNL1 →	+3.977	+0.033	.007	<.001	3	1
SOFT_TISSUE	DMP1 →	+4.392	+0.040	.004	<.001	3	1
SOFT_TISSUE	ZIM2 →	+4.977	+0.050	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

TSPY3 survival (RNA) · tumor vs normal (RNA) · all TSPY3 data types