TSPY26P

Across TCGA pan-cancer cohorts, TSPY26P RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated TSPY26P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TSPY26P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TSPY26P expression acts as an unfavorable survival marker, although some lineages such as HNSC and UVM show a favorable association.

HNSC, STAD, and UVM are the cancer types where TSPY26P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.743	0.576	<.001	97	view →
STAD	OS	Tertile	II,III,IV	0.362	0.634	.002	82	view →
UVM	DFS	Median	III,IV	0.750	0.340	<.001	80	view →
BRCA	DFS	Tertile	III,IV	0.921	0.782	.002	56	view →
LGG	OS	Tertile	All	0.549	0.299	<.001	39	view →
UCEC	DFS	Quartile	IV	0.944	0.537	.011	24	view →
LUAD	OS	Median	III,IV	0.465	0.188	.008	21	view →
KIRC	DFS	Median	All	0.857	0.732	.005	20	view →
BLCA	OS	Quartile	III,IV	0.308	0.607	.007	19	view →
SKCM	OS	Median	II,III,IV	0.799	0.882	.007	17	view →
CHOL	DFS	Median	II,III,IV	0.554	0.116	.010	17	view →
THYM	DFS	Tertile	II,III,IV	0.832	0.472	.005	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

TSPY26P–HNSC (DFS)

Open the HNSC breakdown →