TSPY10

Across TCGA cell cohorts, TSPY10 RNA expression is significantly associated with the mutation status of many other genes, with 54 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TSPY10-associated genes across cancer lineages are KCNQ2, FAT2, and HEATR5A. Each is linked with TSPY10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPY10-to-partner and partner-to-TSPY10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNQ2 grouped by TSPY10-low versus TSPY10-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPY10→partner) and Y-score (partner→TSPY10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	KCNQ2 →	+4.643	+0.226	.008	.002	3	2
OESOPHAGUS	FAT2 →	+2.432	+0.028	.008	.001	3	1
PANCREAS	HEATR5A →	+4.614	+0.040	.004	<.001	3	1
PANCREAS	SAMD11 →	+5.614	+0.053	.002	<.001	3	1
PANCREAS	NBR1 →	+4.029	+0.032	.007	<.001	3	1
OESOPHAGUS	ACSBG1 →	+4.017	+0.050	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

KCNQ2 by TSPY10 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →