TSPY1

Across TCGA patient cohorts, TSPY1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,530 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible TSPY1-associated GO terms across cancer lineages are Positive regulation of double-strand break repair via nonhomologous end joining, Blastocyst development, and Mitochondrial gene expression. Each is linked with TSPY1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TSPY1-to-partner and partner-to-TSPY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair via nonhomologous end joining grouped by TSPY1-low versus TSPY1-high in LGG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPY1→partner) and Y-score (partner→TSPY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Positive regulation of double-strand break repair via nonhomologous end joining →	+0.030	+0.001	.006	.003	3	3
LUAD	Blastocyst development →	+0.021	+0.127	.004	<.001	3	3
TGCT	Mitochondrial gene expression →	+0.024	+1.320	<.001	.001	3	2
LIHC	Regulation of signal transduction by p53 class mediator →	+0.017	+0.157	<.001	<.001	3	2
LIHC	Regulation of cell cycle checkpoint →	+0.038	+0.146	<.001	.002	3	2
LIHC	Protein localization to condensed chromosome →	+0.039	+0.115	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,530 associations by consensus.

Positive regulation of double-strand break repair via nonhomologous end joining by TSPY1 expression — LGG

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