TSPO2

Across TCGA patient cohorts, TSPO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,138 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TSPO2-associated GO terms across cancer lineages are Glycerophospholipid metabolic process, Golgi organization, and Vacuolar transport. Each is linked with TSPO2 in more than 25 cancer types. Because this analysis shows association rather than direction, both TSPO2-to-partner and partner-to-TSPO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerophospholipid metabolic process grouped by TSPO2-low versus TSPO2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPO2→partner) and Y-score (partner→TSPO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Glycerophospholipid metabolic process →	+0.046	+0.303	.006	<.001	2	26
DLBC	Golgi organization →	+0.042	+0.232	.005	<.001	3	25
DLBC	Vacuolar transport →	+0.075	+0.351	<.001	.002	3	25
SCLC	Regulation of double-strand break repair →	+0.042	+0.343	.002	.002	2	26
LAML	Vesicle-mediated transport to the plasma membrane →	+0.045	+0.859	<.001	<.001	3	25
DLBC	Regulation of chromosome organization →	+0.088	+0.231	<.001	.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,138 associations by consensus.

Glycerophospholipid metabolic process by TSPO2 expression — DLBC

Explore this box plot interactively →