TSPAN9

Across TCGA patient cohorts, TSPAN9 protein abundance is significantly associated with the RNA expression of many other genes, with 19,355 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TSPAN9-associated genes across cancer lineages are PRICKLE1, EDNRA, and SDC2. Each is linked with TSPAN9 in more than 5 cancer types. Because this analysis shows association rather than direction, both TSPAN9-to-partner and partner-to-TSPAN9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPAN9 versus PRICKLE1 in UCEC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN9→partner) and Y-score (partner→TSPAN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRICKLE1 →	+0.733	+0.308	<.001	.009	3	6
COAD	EDNRA →	+0.802	+0.329	<.001	.001	3	5
LUAD	SDC2 →	+0.787	+0.307	.001	.001	3	5
COAD	MSRB3 →	+1.408	+0.467	<.001	<.001	3	5
HNSC	FIBIN →	+1.001	+0.282	<.001	.006	3	5
LSCC	ADAMTS12 →	+1.007	+0.448	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,355 associations by consensus.

TSPAN9 vs PRICKLE1 — UCEC

Explore this scatter interactively →