TSPAN9

Across TCGA cell cohorts, TSPAN9 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPAN9-associated genes across cancer lineages are RNASE8 and FAM205A. Each is linked with TSPAN9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN9-to-partner and partner-to-TSPAN9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASE8 grouped by TSPAN9-low versus TSPAN9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN9→partner) and Y-score (partner→TSPAN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RNASE8 →	+0.042	+3.345	<.001	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.033	+5.029	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

RNASE8 by TSPAN9 expression — LARGE_INTESTINE

Explore this box plot interactively →