TSPAN7

Across TCGA cell cohorts, TSPAN7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,192 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPAN7-associated GO terms across cancer lineages are Polyketide metabolic process, Daunorubicin metabolic process, and Doxorubicin metabolic process. Each is linked with TSPAN7 in more than 9 cancer types. Because this analysis shows association rather than direction, both TSPAN7-to-partner and partner-to-TSPAN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Polyketide metabolic process grouped by TSPAN7-low versus TSPAN7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN7→partner) and Y-score (partner→TSPAN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Polyketide metabolic process →	+0.457	+3.614	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Daunorubicin metabolic process →	+0.451	+3.614	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Doxorubicin metabolic process →	+0.457	+3.614	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Pyridine-containing compound metabolic process →	+0.074	+3.402	.001	.002	3	10
LUNG_NSCLC_LUSC	Electron transport chain →	+0.096	+3.125	<.001	.002	3	10
STOMACH	Tetrapyrrole biosynthetic process →	+0.094	+1.803	.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,192 associations by consensus.

Polyketide metabolic process by TSPAN7 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →