TSPAN5

Across TCGA patient cohorts, TSPAN5 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,874 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TSPAN5-associated proteins across cancer lineages are FRMD6_S544, COL3A1, and MYO1B. Each is linked with TSPAN5 in more than 4 cancer types. Because this analysis shows association rather than direction, both TSPAN5-to-partner and partner-to-TSPAN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPAN5 versus FRMD6_S544 in UCEC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN5→partner) and Y-score (partner→TSPAN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FRMD6_S544 →	+0.683	+0.857	<.001	.002	3	5
CCRCC	COL3A1 →	+0.522	+0.319	.001	.004	3	4
CCRCC	MYO1B →	+0.356	+0.422	<.001	<.001	3	4
UCEC	PALD1 →	+0.473	+1.120	<.001	<.001	3	4
LSCC	PLEK2 →	+0.575	+0.495	<.001	.004	3	4
HNSC	PXN →	+0.271	+0.485	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,874 associations by consensus.

TSPAN5 vs FRMD6_S544 — UCEC

Explore this scatter interactively →