TSPAN5

Across TCGA cell cohorts, TSPAN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,666 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TSPAN5-associated GO terms across cancer lineages are Micturition, Actin filament depolymerization, and Positive regulation of ferroptosis. Each is linked with TSPAN5 in more than 10 cancer types. Because this analysis shows association rather than direction, both TSPAN5-to-partner and partner-to-TSPAN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Micturition grouped by TSPAN5-low versus TSPAN5-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN5→partner) and Y-score (partner→TSPAN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Micturition →	+1.802	+2.690	.007	.001	2	11
LIVER	Actin filament depolymerization →	+0.175	+2.177	<.001	<.001	3	10
KIDNEY	Positive regulation of ferroptosis →	+0.197	+1.920	<.001	<.001	3	10
BONE	Glycosaminoglycan catabolic process →	+0.222	+1.680	<.001	.006	3	10
SOFT_TISSUE	Regulation of protein localization to mitochondrion →	+0.112	+2.782	<.001	<.001	3	10
SOFT_TISSUE	Neuron projection maintenance →	+0.149	+2.176	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,666 associations by consensus.

Micturition by TSPAN5 expression — LIVER

Explore this box plot interactively →