Across TCGA patient cohorts, TSPAN4 protein abundance is significantly associated with the RNA expression of many other genes, with 5,507 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSPAN4-associated genes across cancer lineages are RPS12, LILRB3, and COIL. Each is linked with TSPAN4 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSPAN4-to-partner and partner-to-TSPAN4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN4→partner) and Y-score (partner→TSPAN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RPS12 →	-0.820	-0.714	.001	.004	3	3
PDAC	LILRB3 →	+0.777	+0.441	<.001	<.001	3	3
LSCC	COIL →	-0.533	-0.374	<.001	<.001	3	3
HNSC	KLF2 →	+1.050	+0.615	.005	<.001	3	3
UCEC	AMFR →	-0.638	-1.062	.003	.007	3	2
UCEC	UCN →	-1.496	-1.089	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,507 associations by consensus.

Exploration

TSPAN4 survival (RNA) · tumor vs normal (RNA) · all TSPAN4 data types