Across TCGA patient cohorts, TSPAN4 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPAN4-associated genes across cancer lineages are UBE2V1P4, GOLGA6L11P, and MIR4441. Each is linked with TSPAN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN4-to-partner and partner-to-TSPAN4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN4→partner) and Y-score (partner→TSPAN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	UBE2V1P4 →	+0.181	+5.103	<.001	.008	3	2
UCEC	GOLGA6L11P →	+0.027	+4.292	<.001	.006	3	2
STAD	MIR4441 →	+0.387	+4.290	<.001	.008	3	2
CESC	CBY1P1 →	+0.118	+5.010	<.001	.009	3	1
CESC	LINC02024 →	+0.082	+5.010	.003	.009	3	1
CESC	ANOS2P →	+0.025	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

TSPAN4 survival (RNA) · tumor vs normal (RNA) · all TSPAN4 data types