TSPAN33

Across TCGA patient cohorts, TSPAN33 mutation is significantly associated with the RNA expression of many other genes, with 868 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPAN33-associated genes across cancer lineages are MIR6864, RN7SL478P, and MIR3651. Each is linked with TSPAN33 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN33-to-partner and partner-to-TSPAN33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6864 grouped by TSPAN33-low versus TSPAN33-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN33→partner) and Y-score (partner→TSPAN33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6864 →	+0.652	+1.931	<.001	.009	3	2
UCEC	RN7SL478P →	+0.191	+2.161	.008	.005	3	2
SKCM	MIR3651 →	+0.682	+4.057	<.001	.001	3	2
SKCM	UGT2B10 →	+0.252	+4.432	<.001	<.001	3	2
UCEC	YTHDF3-AS1 →	+0.890	+3.609	<.001	.001	3	1
UCEC	SNRPGP17 →	+0.377	+2.463	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 868 associations by consensus.

MIR6864 by TSPAN33 expression — UCEC

Explore this box plot interactively →