TSPAN33

Across TCGA cell cohorts, TSPAN33 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPAN33-associated genes across cancer lineages are CFHR2, UBQLN3, and ACSM6. Each is linked with TSPAN33 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN33-to-partner and partner-to-TSPAN33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by TSPAN33-low versus TSPAN33-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN33→partner) and Y-score (partner→TSPAN33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFHR2 →	+0.057	+5.022	<.001	.002	3	1
SKIN	UBQLN3 →	+0.016	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ACSM6 →	+0.032	+4.169	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CFHR2 by TSPAN33 expression — LARGE_INTESTINE

Explore this box plot interactively →