TSPAN31

Across TCGA pan-cancer cohorts, TSPAN31 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TSPAN31 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TSPAN31 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TSPAN31 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where TSPAN31 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.379	0.666	.003	26	view →
CCRCC	DFS	Quartile	All	0.663	0.961	.002	16	view →
LSCC	DFS	Quartile	II,III,IV	0.494	0.898	.003	13	view →
LUAD	DFS	Median	All	0.484	0.716	.023	6	view →
UCEC	OS	Tertile	III,IV	0.840	0.539	.049	4	view →
GBM	DFS	Tertile	All	0.544	0.800	.024	4	view →
HNSC	DFS	Median	All	0.923	0.987	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TSPAN31–PDAC (OS)

Open the PDAC breakdown →