TSPAN31

Across TCGA pan-cancer cohorts, TSPAN31 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TSPAN31’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TSPAN31 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types TSPAN31 is over-expressed in tumor, although a few such as COAD and PDAC show the opposite, repressed pattern.

COAD, LUAD, and PDAC are the cancer types where TSPAN31 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TSPAN31 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	−0.380	<.001	9	view →
LUAD	Male	All	+0.545	<.001	7	view →
PDAC	Female	All	−1.088	<.001	6	view →
CCRCC	All	All	−0.332	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

TSPAN31–COAD

Open the COAD breakdown →