TSPAN31

Across TCGA patient cohorts, TSPAN31 protein abundance is significantly associated with the RNA expression of many other genes, with 20,287 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSPAN31-associated genes across cancer lineages are DNA2, MRPL9, and WDHD1. Each is linked with TSPAN31 in more than 5 cancer types. Because this analysis shows association rather than direction, both TSPAN31-to-partner and partner-to-TSPAN31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPAN31 versus DNA2 in LSCC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN31→partner) and Y-score (partner→TSPAN31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNA2 →	-0.926	-0.473	<.001	<.001	3	6
UCEC	MRPL9 →	-0.718	-0.610	<.001	.001	3	6
UCEC	WDHD1 →	-0.765	-0.622	<.001	.001	3	6
UCEC	NEK2 →	-1.164	-0.617	.001	.002	3	5
UCEC	DAP3 →	-0.498	-0.539	.002	<.001	3	5
LSCC	ISG20L2 →	-0.410	-0.284	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,287 associations by consensus.

TSPAN31 vs DNA2 — LSCC

Explore this scatter interactively →