TSPAN31

Across TCGA cell cohorts, TSPAN31 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,767 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TSPAN31-associated GO terms across cancer lineages are Endoplasmic reticulum unfolded protein response, Meiotic chromosome segregation, and ER-nucleus signaling pathway. Each is linked with TSPAN31 in more than 11 cancer types. Because this analysis shows association rather than direction, both TSPAN31-to-partner and partner-to-TSPAN31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum unfolded protein response grouped by TSPAN31-low versus TSPAN31-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN31→partner) and Y-score (partner→TSPAN31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Endoplasmic reticulum unfolded protein response →	+0.114	+1.704	<.001	<.001	3	12
OESOPHAGUS	Meiotic chromosome segregation →	-0.186	-1.174	<.001	.001	3	12
STOMACH	ER-nucleus signaling pathway →	+0.109	+0.947	<.001	<.001	3	12
LARGE_INTESTINE	Negative regulation of respiratory burst involved in inflammatory response →	+0.073	+0.865	.001	<.001	2	12
LARGE_INTESTINE	Negative regulation of respiratory burst →	+0.073	+0.865	.001	<.001	2	12
STOMACH	Process utilizing autophagic mechanism →	+0.073	+0.862	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,767 associations by consensus.

Endoplasmic reticulum unfolded protein response by TSPAN31 expression — PANCREAS

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