TSPAN31

Across TCGA cell cohorts, TSPAN31 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPAN31-associated genes across cancer lineages are TCF21, KERA, and LRIT1. Each is linked with TSPAN31 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN31-to-partner and partner-to-TSPAN31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCF21 grouped by TSPAN31-low versus TSPAN31-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN31→partner) and Y-score (partner→TSPAN31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TCF21 →	+0.010	+3.705	<.001	.007	3	1
BLOOD_Leukemia	KERA →	+0.007	+4.966	<.001	<.001	3	1
BLOOD_Leukemia	LRIT1 →	+0.032	+4.269	<.001	.002	3	1
BLOOD_Leukemia	C8orf34 →	+0.129	+3.769	<.001	.008	3	1
BLOOD_Leukemia	C10orf53 →	+0.188	+4.133	<.001	.003	3	1
BLOOD_Leukemia	OR10Q1 →	+0.013	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TCF21 by TSPAN31 expression — BLOOD_Leukemia

Explore this box plot interactively →