TSPAN3

Across TCGA patient cohorts, TSPAN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,094 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TSPAN3-associated proteins across cancer lineages are KRT8, ARFGEF3_S2081, and RPL3. Each is linked with TSPAN3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TSPAN3-to-partner and partner-to-TSPAN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPAN3 versus KRT8 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN3→partner) and Y-score (partner→TSPAN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KRT8 →	+0.685	+0.700	<.001	<.001	2	7
LSCC	ARFGEF3_S2081 →	+0.695	+0.409	.003	.005	3	5
GBM	RPL3 →	-0.326	-0.426	<.001	<.001	3	5
GBM	SPTBN1 →	+0.287	+0.349	<.001	<.001	3	5
LSCC	PLS1 →	+0.607	+0.603	<.001	<.001	3	5
UCEC	TPPP3 →	+1.178	+0.410	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,094 associations by consensus.

TSPAN3 vs KRT8 — OV

Explore this scatter interactively →