TSPAN18

Across TCGA cell cohorts, TSPAN18 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,957 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TSPAN18-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of syncytium formation by plasma membrane fusion, and Transcription initiation at RNA polymerase II promoter. Each is linked with TSPAN18 in more than 10 cancer types. Because this analysis shows association rather than direction, both TSPAN18-to-partner and partner-to-TSPAN18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by TSPAN18-low versus TSPAN18-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN18→partner) and Y-score (partner→TSPAN18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.101	+1.011	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.146	+1.089	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.074	+0.864	<.001	.003	3	11
LUNG_NSCLC_LUSC	Protein-DNA complex organization →	+0.060	+2.351	.008	.003	3	10
OESOPHAGUS	Nucleocytoplasmic transport →	+0.078	+1.641	.002	.001	2	11
OESOPHAGUS	Nuclear transport →	+0.078	+1.641	.002	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,957 associations by consensus.

Cytoplasmic translation by TSPAN18 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →