TSPAN18-AS1

Across TCGA pan-cancer cohorts, TSPAN18-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated TSPAN18-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher TSPAN18-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TSPAN18-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

MESO, LIHC, and COAD are the cancer types where TSPAN18-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.194	0.606	<.001	99	view →
LIHC	OS	Tertile	All	0.148	0.786	<.001	63	view →
COAD	OS	Tertile	All	0.228	0.810	<.001	54	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	45	view →
DLBC	OS	Tertile	All	0.053	0.936	<.001	27	view →
SKCM	OS	Tertile	III,IV	0.179	0.801	<.001	27	view →
HNSC	DFS	Tertile	II,III,IV	0.835	0.669	.016	27	view →
UCS	OS	Tertile	II,III,IV	0.637	0.280	.020	26	view →
THCA	DFS	Tertile	II,III,IV	0.794	0.912	.030	24	view →
TGCT	DFS	Quartile	II,III,IV	0.616	1.000	.013	22	view →
BLCA	DFS	Tertile	All	0.238	0.500	.020	12	view →
UCEC	OS	Tertile	III,IV	1.000	0.558	.043	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

TSPAN18-AS1–MESO (OS)

Open the MESO breakdown →