TSPAN16

Across TCGA patient cohorts, TSPAN16 mutation is significantly associated with the immune_cell of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPAN16-associated genes across cancer lineages are Epithelial cells, Erythrocytes, and NKT. Each is linked with TSPAN16 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN16-to-partner and partner-to-TSPAN16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by TSPAN16-low versus TSPAN16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN16→partner) and Y-score (partner→TSPAN16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.090	-2.115	.004	.019	3	2
UCEC	Erythrocytes →	+0.038	+2.180	<.001	.034	3	2
UCEC	NKT →	-0.105	-2.311	.024	.034	3	2
UCEC	Endothelial cells →	-0.033	-2.991	.048	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.027	-3.660	.010	.001	3	1
UCEC	mv Endothelial cells →	-0.026	-3.459	.011	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Epithelial cells by TSPAN16 expression — UCEC

Explore this box plot interactively →