TSPAN16

Across TCGA cell cohorts, TSPAN16 RNA expression is significantly associated with the go_rna of many other GO terms, with 581 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPAN16-associated GO terms across cancer lineages are Response to selenium ion, Lymphocyte homeostasis, and Sperm-egg recognition. Each is linked with TSPAN16 in more than 3 cancer types. Because this analysis shows association rather than direction, both TSPAN16-to-partner and partner-to-TSPAN16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to selenium ion grouped by TSPAN16-low versus TSPAN16-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN16→partner) and Y-score (partner→TSPAN16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Response to selenium ion →	+0.108	+0.066	<.001	.006	3	3
BLOOD_Leukemia	Lymphocyte homeostasis →	-0.043	-0.064	.005	.008	3	3
BLOOD_Leukemia	Sperm-egg recognition →	-0.120	-0.102	<.001	.009	3	3
BLOOD_Lymphoma	CAMP/PKA signal transduction →	+0.096	+0.017	.002	.005	3	3
OVARY	Negative regulation of collagen metabolic process →	-0.146	-0.028	<.001	.001	3	3
OVARY	Glycolipid transport →	+0.070	+0.025	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 581 associations by consensus.

Response to selenium ion by TSPAN16 expression — BLOOD_Leukemia

Explore this box plot interactively →