TSPAN15

Across TCGA patient cohorts, TSPAN15 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,022 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TSPAN15-associated proteins across cancer lineages are PLEKHA6, PLS1, and SPTLC2. Each is linked with TSPAN15 in more than 5 cancer types. Because this analysis shows association rather than direction, both TSPAN15-to-partner and partner-to-TSPAN15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPAN15 versus PLEKHA6 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN15→partner) and Y-score (partner→TSPAN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHA6 →	+0.606	+0.718	.001	<.001	3	6
LSCC	PLS1 →	+0.466	+0.503	<.001	.001	3	6
BRCA	SPTLC2 →	+0.470	+0.949	<.001	<.001	3	5
COAD	CCDC186 →	+0.270	+0.432	.002	<.001	3	5
LSCC	CCDC6 →	+0.268	+0.647	<.001	.001	3	5
GBM	SHTN1 →	+0.529	+0.706	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,022 associations by consensus.

TSPAN15 vs PLEKHA6 — LSCC

Explore this scatter interactively →