TSPAN15

Across TCGA patient cohorts, TSPAN15 protein abundance is significantly associated with the RNA expression of many other genes, with 12,873 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TSPAN15-associated genes across cancer lineages are CYP3A5, SCP2, and LIPH. Each is linked with TSPAN15 in more than 4 cancer types. Because this analysis shows association rather than direction, both TSPAN15-to-partner and partner-to-TSPAN15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPAN15 versus CYP3A5 in LUAD, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN15→partner) and Y-score (partner→TSPAN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CYP3A5 →	+1.043	+0.455	.003	.006	3	5
BRCA	SCP2 →	+0.529	+0.492	<.001	<.001	3	5
BRCA	LIPH →	+1.234	+0.678	<.001	<.001	3	5
BRCA	C9orf152 →	+1.999	+0.664	<.001	<.001	3	5
COAD	ST6GALNAC1 →	+2.034	+0.466	<.001	<.001	3	5
COAD	MEDAG →	-1.411	-0.425	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,873 associations by consensus.

TSPAN15 vs CYP3A5 — LUAD

Explore this scatter interactively →