TSPAN15

Across TCGA cell cohorts, TSPAN15 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPAN15-associated genes across cancer lineages are OR2M2, HTR1B, and OR4F5. Each is linked with TSPAN15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN15-to-partner and partner-to-TSPAN15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M2 grouped by TSPAN15-low versus TSPAN15-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN15→partner) and Y-score (partner→TSPAN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2M2 →	+0.013	+5.807	<.001	.001	3	1
LARGE_INTESTINE	HTR1B →	+0.068	+4.029	<.001	.004	3	1
LARGE_INTESTINE	OR4F5 →	+0.029	+3.930	<.001	.003	3	1
LARGE_INTESTINE	FAM24A →	+0.050	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR2M2 by TSPAN15 expression — OVARY

Explore this box plot interactively →