TSPAN15

Across TCGA cell cohorts, TSPAN15 mutation is significantly associated with the mutation status of many other genes, with 776 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPAN15-associated genes across cancer lineages are ANOS1, ADAMTS2, and BAIAP3. Each is linked with TSPAN15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN15-to-partner and partner-to-TSPAN15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANOS1 grouped by TSPAN15-low versus TSPAN15-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN15→partner) and Y-score (partner→TSPAN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ANOS1 →	+5.824	+5.824	.002	.002	1	2
LARGE_INTESTINE	ADAMTS2 →	+2.284	+3.925	.005	.005	1	2
LARGE_INTESTINE	BAIAP3 →	+3.159	+4.632	<.001	<.001	1	2
SKIN	BCKDHB →	+4.824	+5.392	.004	.004	1	2
OVARY	GAS8 →	+4.977	+4.415	.007	.007	1	2
SKIN	HIRA →	+4.824	+5.392	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 776 associations by consensus.

ANOS1 by TSPAN15 expression — SKIN

Explore this box plot interactively →