TSPAN14

Across TCGA patient cohorts, TSPAN14 mutation is significantly associated with the RNA expression of many other genes, with 3,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPAN14-associated genes across cancer lineages are RNU5F-3P, MIR769, and KCND3-IT1. Each is linked with TSPAN14 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN14-to-partner and partner-to-TSPAN14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5F-3P grouped by TSPAN14-low versus TSPAN14-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN14→partner) and Y-score (partner→TSPAN14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU5F-3P →	+0.586	+5.877	<.001	<.001	3	2
COAD	MIR769 →	+0.291	+3.843	.003	.004	3	2
COAD	KCND3-IT1 →	+0.261	+3.843	.005	.004	3	2
COAD	RN7SL72P →	+0.102	+4.251	<.001	.008	3	2
COAD	MIR3126 →	+0.789	+4.547	<.001	.005	3	2
UCEC	RPS29P32 →	+0.262	+2.097	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,277 associations by consensus.

RNU5F-3P by TSPAN14 expression — SKCM

Explore this box plot interactively →