TSPAN14

Across TCGA cell cohorts, TSPAN14 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPAN14-associated genes across cancer lineages are SMIM32 and ADAM7. Each is linked with TSPAN14 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN14-to-partner and partner-to-TSPAN14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM32 grouped by TSPAN14-low versus TSPAN14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN14→partner) and Y-score (partner→TSPAN14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SMIM32 →	+0.023	+3.584	<.001	.003	3	1
LARGE_INTESTINE	ADAM7 →	+0.005	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SMIM32 by TSPAN14 expression — BLOOD_Leukemia

Explore this box plot interactively →