TSPAN13

Across TCGA pan-cancer cohorts, TSPAN13 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TSPAN13 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TSPAN13 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TSPAN13 expression acts as an unfavorable survival marker.

CCRCC, COAD, and PDAC are the cancer types where TSPAN13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.695	1.000	.001	56	view →
COAD	DFS	Quartile	II,III,IV	0.907	1.000	.038	12	view →
PDAC	OS	Median	IV	0.381	0.951	.006	12	view →
LUAD	DFS	Tertile	All	0.687	0.874	.011	7	view →
OV	DFS	Quartile	All	0.652	1.000	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TSPAN13–CCRCC (OS)

Open the CCRCC breakdown →