TSPAN13

Across TCGA cell cohorts, TSPAN13 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TSPAN13-associated genes across cancer lineages are TSPY3, C1orf232, and PRM1. Each is linked with TSPAN13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN13-to-partner and partner-to-TSPAN13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY3 grouped by TSPAN13-low versus TSPAN13-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN13→partner) and Y-score (partner→TSPAN13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	TSPY3 →	+0.626	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	C1orf232 →	+0.084	+4.736	<.001	.009	3	1
LARGE_INTESTINE	PRM1 →	+0.691	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR10R2 →	+0.031	+4.977	<.001	.007	3	1
LARGE_INTESTINE	SCYGR2 →	+0.086	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TSPY3 by TSPAN13 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →