TSPAN11

Across TCGA patient cohorts, TSPAN11 mutation is significantly associated with the RNA expression of many other genes, with 127 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSPAN11-associated genes across cancer lineages are MIR302A, LINC01038, and RNA5SP131. Each is linked with TSPAN11 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN11-to-partner and partner-to-TSPAN11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR302A grouped by TSPAN11-low versus TSPAN11-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN11→partner) and Y-score (partner→TSPAN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR302A →	+0.779	+4.293	<.001	.003	3	2
LUAD	LINC01038 →	+0.052	+6.339	<.001	<.001	3	2
UCEC	RNA5SP131 →	+0.473	+3.551	<.001	.004	3	2
UCEC	NDUFS5P5 →	+0.240	+3.063	<.001	.002	3	2
LUSC	MIR1179 →	+0.458	+8.336	<.001	<.001	3	2
LUSC	MIR4253 →	+0.593	+5.093	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

MIR302A by TSPAN11 expression — LUAD

Explore this box plot interactively →