TSNAXIP1

Across TCGA patient cohorts, TSNAXIP1 mutation is significantly associated with the RNA expression of many other genes, with 1,528 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSNAXIP1-associated genes across cancer lineages are TRAV40, RNU6-229P, and MIR5088. Each is linked with TSNAXIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSNAXIP1-to-partner and partner-to-TSNAXIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAV40 grouped by TSNAXIP1-low versus TSNAXIP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSNAXIP1→partner) and Y-score (partner→TSNAXIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAV40 →	+0.220	+3.154	.003	.006	3	2
COAD	RNU6-229P →	+0.264	+4.821	<.001	.003	3	2
COAD	MIR5088 →	+0.304	+4.595	<.001	.004	3	2
HNSC	CENPVL3 →	+0.304	+4.498	<.001	.002	3	2
CESC	OR7E101P →	+0.322	+4.705	<.001	.003	3	2
CESC	LARP1BP1 →	+0.117	+4.539	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,528 associations by consensus.

TRAV40 by TSNAXIP1 expression — COAD

Explore this box plot interactively →