TSNAXIP1

Across TCGA cell cohorts, TSNAXIP1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSNAXIP1-associated genes across cancer lineages are TNP1, MCHR2, and MTNR1A. Each is linked with TSNAXIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSNAXIP1-to-partner and partner-to-TSNAXIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by TSNAXIP1-low versus TSNAXIP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSNAXIP1→partner) and Y-score (partner→TSNAXIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TNP1 →	+0.167	+5.569	<.001	.001	3	1
BLOOD_Leukemia	MCHR2 →	+0.034	+4.539	<.001	.007	3	1
BLOOD_Leukemia	MTNR1A →	+0.137	+4.409	<.001	.005	3	1
BLOOD_Leukemia	WFDC11 →	+0.030	+4.539	<.001	.007	3	1
BLOOD_Leukemia	STH →	+0.084	+4.874	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TNP1 by TSNAXIP1 expression — BLOOD_Leukemia

Explore this box plot interactively →