TSHZ1

Across TCGA pan-cancer cohorts, TSHZ1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TSHZ1 data layer compared with 22 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TSHZ1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TSHZ1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

PDAC and LUAD are the cancer types where TSHZ1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	II,III,IV	0.423	0.935	<.001	51	view →
LUAD	DFS	Median	All	1.000	0.306	.002	10	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TSHZ1–PDAC (DFS)

Open the PDAC breakdown →