TSHZ1

Across TCGA cell cohorts, TSHZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,380 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TSHZ1-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Regulation of androgen receptor signaling pathway, and Regulation of cell cycle G1/S phase transition. Each is linked with TSHZ1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TSHZ1-to-partner and partner-to-TSHZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by TSHZ1-low versus TSHZ1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSHZ1→partner) and Y-score (partner→TSHZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.108	+1.262	<.001	.002	3	12
LUNG_SCLC	Regulation of androgen receptor signaling pathway →	+0.113	+1.650	<.001	<.001	3	11
LUNG_SCLC	Regulation of cell cycle G1/S phase transition →	+0.062	+1.228	.001	.003	3	10
LUNG_SCLC	Regulation of G1/S transition of mitotic cell cycle →	+0.059	+1.088	.002	.007	3	10
LUNG_SCLC	Regulation of mitotic cytokinesis →	+0.151	+2.019	<.001	<.001	3	10
LUNG_SCLC	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.148	+1.626	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,380 associations by consensus.

Regulation of nucleotide-excision repair by TSHZ1 expression — LUNG_SCLC

Explore this box plot interactively →