TSGA10IP

Across TCGA pan-cancer cohorts, TSGA10IP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TSGA10IP data layer compared with 23 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher TSGA10IP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TSGA10IP expression acts as an unfavorable survival marker.

LGG, READ, and KICH are the cancer types where TSGA10IP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.195	0.897	<.001	18	view →
READ	OS	Median	III,IV	0.287	0.748	.001	15	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
SKCM	DFS	Median	III,IV	0.137	0.654	.010	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TSGA10IP–LGG (OS)

Open the LGG breakdown →