TSGA10

Across TCGA patient cohorts, TSGA10 protein abundance is significantly associated with the RNA expression of many other genes, with 9,777 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSGA10-associated genes across cancer lineages are SPEF1, GIPR, and OIP5. Each is linked with TSGA10 in more than 2 cancer types. Because this analysis shows association rather than direction, both TSGA10-to-partner and partner-to-TSGA10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSGA10 versus SPEF1 in UCEC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSGA10→partner) and Y-score (partner→TSGA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPEF1 →	+1.684	+0.898	<.001	<.001	3	3
UCEC	GIPR →	+1.000	+1.182	<.001	<.001	3	3
UCEC	OIP5 →	-0.889	-0.979	<.001	.001	3	3
UCEC	RP1 →	+1.774	+1.176	<.001	<.001	3	3
UCEC	CCDC114 →	+1.852	+1.309	<.001	<.001	3	3
UCEC	CAPS →	+2.013	+1.491	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,777 associations by consensus.

TSGA10 vs SPEF1 — UCEC

Explore this scatter interactively →