TSEN34

Across TCGA cell cohorts, TSEN34 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,847 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TSEN34-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Regulation of anaphase-promoting complex-dependent catabolic process, and Negative regulation of myoblast fusion. Each is linked with TSEN34 in more than 13 cancer types. Because this analysis shows association rather than direction, both TSEN34-to-partner and partner-to-TSEN34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by TSEN34-low versus TSEN34-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSEN34→partner) and Y-score (partner→TSEN34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.067	+0.686	.003	.002	3	14
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.145	+0.469	.001	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.069	+0.677	.007	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of chromatin organization →	+0.064	+0.605	<.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.070	+0.702	.006	<.001	3	9
BONE	ATP metabolic process →	+0.087	+0.615	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,847 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by TSEN34 expression — BREAST

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