TSEN2

Across TCGA patient cohorts, TSEN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,386 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TSEN2-associated proteins across cancer lineages are TOP2B, P4HB, and ADNP. Each is linked with TSEN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TSEN2-to-partner and partner-to-TSEN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSEN2 versus TOP2B in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSEN2→partner) and Y-score (partner→TSEN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TOP2B →	+0.379	+0.556	<.001	<.001	3	8
GBM	P4HB →	-0.451	-0.342	<.001	<.001	3	7
GBM	ADNP →	+0.448	+0.535	<.001	<.001	3	7
OV	KIAA1143 →	+0.581	+0.475	<.001	<.001	3	7
GBM	RBM12 →	+0.266	+0.412	<.001	<.001	3	7
GBM	PNN →	+0.366	+0.398	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,386 associations by consensus.

TSEN2 vs TOP2B — HNSC

Explore this scatter interactively →